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Engineer Therapeutic Microorganisms

Beneficial microorganisms could deliver drugs, fight pathogens, or repair damage in the human body, yet we cannot engineer microbes safely and effectively for therapeutic applications. This challenge involves creating programmable therapeutic microorganisms with precise control and safety features. Barriers include safety concerns, containment mechanisms, therapeutic efficacy, regulatory approval, and public acceptance. Without therapeutic microorganisms, drug delivery will remain imprecise, treatment options will be limited, and the potential of living therapeutics will be unrealized. Success could provide precise drug delivery, create living therapeutics, enable targeted treatments, and revolutionize medicine while offering new therapeutic modalities.

Science, Biology, Microbiology