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Engineer Probiotic Therapeutics

Beneficial bacteria could treat diseases by producing drugs inside the body, yet engineering probiotics for therapeutic applications remains challenging and unpredictable. This challenge involves creating safe and effective probiotic therapeutics with precise control. Barriers include safety considerations, therapeutic efficacy, stability, regulatory approval, and patient acceptance. Without engineered probiotics, therapeutic options will be limited, drug delivery will remain imprecise, and the potential of living medicines will be unrealized. Success could provide living therapeutics, enable precise drug delivery, create personalized probiotic medicines, and revolutionize treatment approaches while advancing probiotic medicine.

Science, Biology, Microbiology