Blocking the inflammatory enzyme caspase-1 reduced lung tumor development in high-risk mice, while combining a caspase-1 inhibitor with an IL-1 beta antibody prevented tumors entirely in nearly 20% of treated mice, suggesting a potential approach for lung cancer prevention.

Blocking the inflammatory enzyme caspase-1 reduced lung tumor development in high-risk mice, while combining a caspase-1 inhibitor with an IL-1 beta antibody prevented tumors entirely in nearly 20% of treated mice, suggesting a potential approach for lung cancer prevention.